4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride
Bendamustine Hydrochloride
CAS: 3543-75-7;97832-05-8
Molecular Formula: C16H21Cl2N3O2.HCl
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride - Names and Identifiers
| Name | Bendamustine Hydrochloride |
| Synonyms | Treanda CYTOSTASAN Bendamustine CytostasanHCl BENDAMUSTINE HCL Phenol,5-iodo-7-methyl- BENDAMUSTIN HYDROCHLORIDE Bendamustine Hydrochloride 1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro 1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride 4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride |
| CAS | 3543-75-7 97832-05-8 |
| InChI | InChI=1/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H |
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride - Physico-chemical Properties
| Molecular Formula | C16H21Cl2N3O2.HCl |
| Molar Mass | 394.72 |
| Melting Point | 149-151°C |
| Boling Point | 585.2°C at 760 mmHg |
| Flash Point | 307.7°C |
| Vapor Presure | 1.55E-14mmHg at 25°C |
| Storage Condition | 2-8℃ |
| MDL | MFCD16879055 |
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride - Introduction
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. Bendamustine activates DNA-damage stress response and apoptosis; inhibits mitotic checkpoints; and induces mitotic catastrophe.
Last Update：2022-10-16 17:24:50
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